1H-Pyrazole-5-carboxaldehyde, 1-methyl-
1-Methyl-1H-pyrazole-5-carbaldehyde
CAS: 27258-33-9
Molecular Formula: C5H6N2O
1H-Pyrazole-5-carboxaldehyde, 1-methyl- - Names and Identifiers
1H-Pyrazole-5-carboxaldehyde, 1-methyl- - Physico-chemical Properties
| Molecular Formula | C5H6N2O |
| Molar Mass | 110.11 |
| Density | 1.118 g/mL at 25 °C |
| Boling Point | 115/15mm |
| Flash Point | 66℃ |
| Vapor Presure | 0.123mmHg at 25°C |
| pKa | 0.56±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | n20/D1.521 |
1H-Pyrazole-5-carboxaldehyde, 1-methyl- - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29331990 |
| Hazard Note | Harmful |
| Hazard Class | IRRITANT |
1H-Pyrazole-5-carboxaldehyde, 1-methyl- - Introduction
It is an organic compound with the chemical formula C6H6N2O. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to pale yellow solid.
-Melting point: About 60-65 ℃.
-Solubility: Soluble in most organic solvents, such as methanol, ethanol and dichloromethane.
Use:
-is an important intermediate in synthesis and organic synthesis. It is widely used in drug synthesis, Pesticide Synthesis, dye synthesis and other fields.
-It can also be used as an organic synthesis reagent to construct the skeleton of complex organic molecules.
Method:
It can be synthesized by the following steps:
1. Pyrazine reacts with methanol to generate 1-methyl -2-(methyloxy) pyridine.
2.1-methyl -2-(methyloxy) pyridine reacts with sodium hydroxide to generate 1-methyl -5H-pyrazole.
3. React 1-methyl -5H-pyrazole with acetaldehyde to produce the final product.
Safety Information:
-. Follow regular laboratory safety procedures when handling.
-It may be irritating to the eyes and skin, so you need to wear protective glasses and gloves during operation.
-During storage and transportation, it needs to be kept dry, protected from light and sealed to prevent it from moisture, deterioration or loss of activity.
Nature:
-Appearance: Colorless to pale yellow solid.
-Melting point: About 60-65 ℃.
-Solubility: Soluble in most organic solvents, such as methanol, ethanol and dichloromethane.
Use:
-is an important intermediate in synthesis and organic synthesis. It is widely used in drug synthesis, Pesticide Synthesis, dye synthesis and other fields.
-It can also be used as an organic synthesis reagent to construct the skeleton of complex organic molecules.
Method:
It can be synthesized by the following steps:
1. Pyrazine reacts with methanol to generate 1-methyl -2-(methyloxy) pyridine.
2.1-methyl -2-(methyloxy) pyridine reacts with sodium hydroxide to generate 1-methyl -5H-pyrazole.
3. React 1-methyl -5H-pyrazole with acetaldehyde to produce the final product.
Safety Information:
-. Follow regular laboratory safety procedures when handling.
-It may be irritating to the eyes and skin, so you need to wear protective glasses and gloves during operation.
-During storage and transportation, it needs to be kept dry, protected from light and sealed to prevent it from moisture, deterioration or loss of activity.
Last Update：2024-04-09 20:49:11
